Local anesthetics have transformed clinical practice by enabling a broad range of minor and major procedures with minimal discomfort. Although adverse reactions are frequently reported, genuine ...

Is local infiltration of an abdominal wound with an anesthetic as effective as epidural anesthesia for the control of postoperative pain? The authors of this article combined the results of 9 ...

Medical researchers bringing surgical patients closer to having a long-acting local anesthetic. In a randomized, double-blind trial, patients given neosaxitoxin, a new local anesthetic derived from ...

A new study has uncovered how the commonly used local anesthetic drug, lidocaine, activates bitter taste receptors to exert an anti-cancer effect in head and neck cancers. Given its low cost and ready ...

The localized loss of sensation with resultant reduction in pain stimuli is the end result of local anesthesia. This mode of anesthesia is considered to be safer than general anesthesia, because it ...

All current local anesthetics block sensory signals—pain—but they also interrupt motor signals, which can be problematic. For example, too much epidural anesthesia can prevent mothers in labor from ...

Liposomal bupivacaine was launched on the market twelve years ago to provide long-lasting local control of pain. The medication is used as a local anesthetic, particularly for orthopedic operations. A ...

Q: Which doctor administers local anesthesia? A: The doctor performing the surgery, either dentists, ophthalmologists or another surgeon will administer the local anesthetic. A: Twilight sedation is ...

A topical mucoadhesive tablet containing the antidepressant amitriptyline significantly reduced pain from needle pricks in a small, randomized controlled clinical trial. The researchers said the ...